Effect of 8 weeks of circuit training on serum Irisin levels and Insulin Resistance Index in overweight girls

The purpose of this study was the effect of eight weeks of circuit training on the Irisin levels and the Insulin Resistance Index (HOMA-IR) in overweight women. Materials and Methods: In this study 22 overweight women voluntarily were chosen (Age 26.04±4.43 yrs, BMI 29.35±2.53 kg/m2) and were divided to two groups of control (n=11) and experimental (n=11). In the experimental group, subjects performed circuit training for eight weeks and four times per week. Blood sample was taken before and 48 hours after the last training session. Statistical analysis at the level of P<0.05 was done. Findings: After eight weeks of training, the level of Irisin in experimental group significantly increased while the HOMA-IR had a significant reduction (p<0.05). Also Pearson correlation co-efficiency test shows that there is a reverse relationship between irisin and HOMA-IR (P≤0.05). Conclusion: It appears that circuit training improves body composition and metabolic disorders such as insulin resistance through Irisin induction in overweight women.